There is no effective known treatment for dementia. But we know a lot about what affects brain function and brain aging: our nutrition, inflammation, environment toxins, stress, exercise and deficiencies of hormones, vitamins and omega-3 fats.
It is not only just one gene but the interaction between many genes and the environment thats someone at risk for a chronic disease such as dementia. And we know that many things affect how our genes function — our diet, vitamins and minerals, toxins, allergens, stress, lack of sleep and exercise, and more. Even though no long-term studies have been done to look at treating dementia based on genes, there are so many scientific threads that weave together a picture of how and why our brains age and what genes are involved.
George had a gene called apo E4, which is a high-risk gene for Alzheimer’s disease(ii) and also made it hard for him to lower his cholesterol and detoxify mercury from his brain.(iii) He also had a version of a gene for detoxification of metals and other toxins (glutathione-S-transferase, or GST)(iv) that was very inefficient, making him accumulate more toxins over his lifetime. Having the combination of a problem with GST and apo E4 puts people at even more risk for dementia.(v),(vi) In another study, people with an absent GST gene were likely to have much higher levels of mercury.(vii)
George had another gene called MTHFR(viii) that made him require very high doses of folate to lower his blood levels of homocysteine, which is a substance very toxic to the brain. Lastly, he had a gene called CETP that caused his cholesterol to be high, which contributes to dementia. Combine this gene with the apo E4 gene and your risk of dementia goes way up.(ix)
We found that George had high levels of mercury(x) and helped him detoxify with foods such as kale, watercress, and cilantro, herbs such as milk thistle, nutrients such as selenium and zinc, and medications that helped him overcome his genetic difficulties by getting rid of toxins. We lowered his cholesterol with diet and herbs. We lowered his homocysteine with high doses of folate and vitamins B6 and B12.
After a year of aggressive therapy that was matched to his genes, not his diagnosis, he had a remarkable and dramatic recovery. Before I saw him, he could not manage his business, nor did his grandchildren want to be around him. After matching his treatment to his genes, he was again able to function, and his grandchildren loved being with him again.
While this area of genetic testing and nutrigenomics is new, and more research is needed to help us refine our understanding and treatment, there are ways to look through new doors into an entirely new era of medicine that no longer focuses on the disease, but on the person and their uniqueness.
A woman named Christine was eighty and was experiencing severe memory loss and cognitive decline. Her family was obviously concerned, so she was tested with hours of neuropsychological testing and found to have dementia. Her neurologist offered her words of comfort, but told her and her family there is no treatment truly effective to stop or reverse the progression of dementia. That’s when her daughter brought her to see me.
We discovered many subtle changes in her health that on their own wouldn’t explain dementia, but when added all together put a strain on her brain function. All we did was correct those problems — low thyroid function, mercury toxicity, inflammation, and deficiencies in vitamins B6 and D, folate, coenzyme Q10, and omega-3 fats — and improved her diet overall. I encouraged her to exercise, because exercise can help improve cognitive function and prevent dementia.
Six months later, she had the extensive memory tests repeated. Her psychologist was surprised to report that her scores got BETTER! To put this in perspective, mental decline happens progressively, sometimes quickly, sometimes slowly, but NEVER gets better — according to our traditional medical thinking.
But just like we once thought that heart disease and artery-clogging plaques couldn’t be reversed (and now have proof that this does happen), I believe dementia can be reversed (if caught early enough) by attending to all the factors that affect brain function – diet, exercise, stress, nutritional deficiencies, toxins, hormonal imbalances, inflammation, and more.
9 Steps to Reversing Dementia
Start by looking hard for correctable causes of memory loss. They include:
- Pre-diabetes or metabolic syndrome
- Low thyroid function
- Depression
- Deficiencies in B vitamins, especially vitamin B12
- Omega-3 fat deficiencies
- Mercury or other heavy metal toxicity
- Vitamin D deficiency
- High cholesterol
- Unique genes that predispose you to nutritional or detoxification problems
Once you identify the underlying causes of the imbalance, here are a few things that can help your mind get a tune-up:
- Balance your blood sugar with a whole foods, low glycemic diet
- Exercise daily — even a 30-minute walk can help
- Deeply relax daily with yoga, meditation, biofeedback, or just deep breathing
- Take a multivitamin and mineral supplement
- Take an omega-3 fat supplement
- Take extra vitamin B6, B12, and folate
- Take vitamin D
- Treat thyroid or low sex hormones
- Get rid of mercury through a medical detoxification program
This article is taken from the website of Dr Hyman (http://drhyman.com/blog/2010/06/14/9-steps-to-reverse-dementia-and-memory-loss-as-you-age-2/) and I hope you will use your discretion to carry out independent verification or consult a specialist for advice before any actions.
Reference: http://drhyman.com/blog/2010/06/14/9-steps-to-reverse-dementia-and-memory-loss-as-you-age-2/
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